Team Science for Dementia: The ADRC Circular Loop (Discovery → Development → Delivery → Dissemination) Harnessing Team Science in Dementia Research: The ADRC Circular Loop Citation: Akter S, Bawa EM, Riccardi N, et al. Journal of Alzheimer’s Disease Reports. 2025;9. doi:10.1177/25424823251385902 Curator: Warren Peters, MD MPH FOMA • Silo: Voice of Health (Research Edition) SEO… Continue reading Harnessing Team Science
Category: Research
Brain Health Beyond Biology
Cognitive health during aging is not just about genes or willpower. It’s about where we’re born, live, learn, work, and age—the social determinants of health (SDOH)—and the policies that shape those conditions. Because social environments and access to resources differ widely, not everyone experiences healthy cognitive aging. This long-form guide synthesizes cutting-edge evidence on SDOH… Continue reading Brain Health Beyond Biology
The Broader Context of Drug Repurposing
Introduction: Shifting the Paradigm in Alzheimer’s Research The landscape of Alzheimer’s disease (AD) research is undergoing a significant transformation. For decades, the focus has been on the amyloid hypothesis, with a multitude of clinical trials targeting amyloid-beta plaques, often with disappointing results. However, recent developments, including the NIA’s strategic funding of novel approaches, signal a… Continue reading The Broader Context of Drug Repurposing
Gait Variability in Parkinson’s Disease: A Researcher White Paper (2022–2025)
Executive Summary Gait variability—particularly stride-time variability (STV) and stride-length variability—has emerged as a promising but context-dependent digital signal for Parkinson’s disease (PD). Across recent studies, STV is repeatedly sensitive to disease state and intervention effects, yet its interpretability hinges on speed control, environment (overground vs treadmill), fatigue, footwear, and surface. Real-world, continuous measurement via wearables… Continue reading Gait Variability in Parkinson’s Disease: A Researcher White Paper (2022–2025)